A patent pending proprietary mango leaf extract ideal for boosting mental and physical energy









Zynamite® for mental & physical energy


Zynamite® is Nektium’s award-winning, patent pending proprietary extract of Mangifera indica standardized to 60% mangiferin.

Zynamite® is the result of a five year long global research quest for the next-generation mental & physical energy ingredient

Zynamite® is an all-natural evidence-based nootropic and sports performance ingredient, supported by seven clinical studies.

Zynamite® is used to energize mental and physical performance formulations.



Zynamite® at a glance
  • 7 clinical studies
  • 5 peer reviewed publications
  • 3 patents pending: for mental energy, sports performance
    and anti-craving
  • 3 global industry awards, for research, innovation, and sports.
  • Fast-acting & long lasting
  • Mechanisms of action entirely different to caffeine
  • Side-effect free
  • Self-affirmed GRAS
  • Natural, clean label





Zynamite® nootropic activities
  • Activates brain electrical activity
  • Increases long term potentiation
  • Faster reaction time and increased calculation performance
  • Decreased fatigue







Zynamite® in sports combinations

Tested in repeat sprint exercise as well as exercise during simulated exhaustion (ischaemia-reperfusion model) in men and women.

  • Increased peak power output
  • Increased mean power output
  • Increased VO2max
  • Increased brain oxygenation in women
  • Increased muscle oxygen extraction
  • Decreased lactate









Push past your limits


Zynamite® is an ingredient that delivers mental energy and supports the mental and physical aspects of sports performance. Clinical studies of formulations containing Zynamite® significantly improves both peak power output and mean power output in fatigued and exhausted men and women – that place where athletes find themselves when they need your help the most.

Faster reaction and quicker adaptation to changing conditions are essential to high performance athletics. The cognitive benefits of Zynamite® combined with the physical make this ingredient a unique solution for athletes, e-sports, shift workers, truck drivers and every person in need of mental and physical energy.

Intriguingly, in vivo studies of Zynamite® have pointed to the potential for synergies between Zynamite® and low doses of caffeine, suggesting that formulations that combine these ingredients will be attractive to consumers. This sets up exciting formulating options that include both ‘stim’ and ‘non-stim’ products.




Peer reviewed publications


Dimpfel, W., et al. Zynamite®(Mangifera indica leaf extract) and Caffeine Act in a Synergistic Manner on Electrophysiological Parameters of Rat Central Nervous System. Food and Nutrition Sciences, 9, 502-518 (2018).

Gelabert-Rebato, M., et al. Enhancement of Exercise Performance by 48 Hours, and 15-Day Supplementation with Mangiferin and Luteolin in Men. Nutrients, 11 (2), 344 (2019).

Gelabert-Rebato, M., et al. Mangifera indica L. leaf Extract (Zynamite®) in Combination with Luteolin or Quercetin Enhances VO2peak and Peak Power Output, and Preserves Skeletal Muscle Function During Ischemia-Reperfusion in Humans. Front. Physiol. 9, 740 (2018).

Gelabert-Rebato, et al. A Single Dose of The Mango Leaf Extract Zynamite® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Nutrients, 11 (11), 2592 (2019).

Reddeman, R.A., et al. A Toxicological Evaluation of Mango Leaf Extract (Mangifera indica) Containing 60% Mangiferin. Journal of toxicology, (2019).




  • Rapid onset of mental activation
  • Faster reaction time
  • Increases performance
  • Sustained energy
  • Increased power
  • Doping free




The information contained in this publication is provided in good faith for B2B customers only, and is based on our current knowledge. No legally binding promise or warranty regarding the suitability of our products for any specific use is made. These statements have not been evaluated by the Food and Drug Administration or by EFSA. This product is not intended to diagnose, treat, cure, or prevent any disease. Nektium Pharma S.L. will not assume any expressed or implied liability in connection with any use of this information.