Unlock your natural calm
Vanizem™ is a fast-acting, non-sedative botanical extract that supports positive mood and provides effective management of day-to-day stress. It has also shown to lower tension, reduce perception of anxiety and elevate mood within just three days.
Vanizem™ is derived from sustained cultivated sourced Aframomum melegueta of West African origin and uses Nektium’s proprietary extraction and bioactive standardization processes in addition to patent-pending encapsulation technologies.
Supported by a clinical crossover study in 30 adults, aged 40 to 50, with mildly elevated stress levels, demonstrated that a low dose within just 3 days showed significant results in improving mental wellbeing, reducing stress and anxiety levels, supporting sleep and contributing to overall relaxation.
Stress and anxiety are in the top three concerns for supplements users globally and managing mental health and well-being is a key priority for many consumers. According to Innova Market Insights, product claims related to brain health and mood were the second top most featured claims in supplements launches globally for the 12 months ending Q1 2023 (Grew globally by 27%).
Botanical solutions developed specifically to meet this demand for improved mental health and well-being have been a priority for Nektium’s R&D team, and this is how Vanizem™ was born. Vanizem™ offers a fast acting, safe and natural solution, without side effects, and acts as an alternative to other products in the markets.
Sustainably sourced plant-based “spice” Aframomum melegueta.
Patent pending, proprietary microencapsulation process that maintains the bioactives stable in time and ensures high efficacy.
Standardized bioactives (10% of total Vanilloids where 1.5% of them are 6-Paradol), targeting the endocannabinoid system.
In a pilot clinical study, daily low-dose Vanizem™ intake for three days reduced the perceived anxiety, improved mood, and enhanced mental wellbeing in thirty participants aged 40 to 50, experiencing daily stress. Vanizem™ also improves sleep quality and no side effects were reported in the study.
Its patent-pending extract targets the endocannabinoid system by inhibiting fatty acid amide hydrolase (FAAH), thereby maintaining anandamide levels, which may regulate mood and anxiety without psychoactive or sedative effects. Additionally, Vanizem™ affects the TRPV1 receptor, known for pain perception and inflammation, and exhibits potential as an agonist for 5-HT1AR and CB2R receptors, suggesting its ability to modulate serotonin pathways and reduce neuroinflammation in response to stress.
Vanizem™ has been developed using a patent-pending microencapsulation technology, which gives it a range of superior properties including improved stability, longer shelf-life, greater efficacy and versatility in formulation.
This process helps to minimize loss of bioactive compounds and ensures the integrity of our final product, preserving its nutraceutical value and efficacy at a low dose.
Did you know?
Aframomum melegueta, also known as Grains of Paradise, has been mainly used in Africa as a spice for seasoning food but also for treating many digestive system issues among others
Aframomum melegueta
Total Vanilloids ≥ 10 %
- 6-paradol ≥ 1,5 %
Cultivated
Nektium Pharma SL holds GMP certification (ES19/85835), FSSC 22000 Food Safety System Certification (ES19/86276) and ISO14001 Environmental Management System certification (ES23/985) by SGS.
The Nektium Guarantee
From our trusted relationships with our suppliers and ensuring responsible sourcing, to how we carefully treat the raw botanicals at our specialist facilities, we are more than just an ingredients supplier.
We truly understand the fingerprint of our branded ingredients and our expert technical team can support you to adapt them for a wide range of specific needs and uses.
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Nektium’s new Vanizem™ botanical extract, derived from the West African spice Aframomum melegueta, can significantly improve mood, reduce stress levels, and enhance sleep quality within just three days, as revealed by a recent pilot study. This placebo-controlled crossover study involved 30 healthy adults aged 40-50, who experienced day-to-day stress. Participants consuming at least 100mg of Vanizem™ saw significant reductions in anxiety and improvements in mood and sleep quality. The extract's efficacy is attributed to its impact on the endocannabinoid system and various receptors related to mood and stress regulation, without causing sedative effects, making it suitable for daily use.
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